Industry leaders launch Actionable Genome Consortium
November 2014
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SAN DIEGO—Illumina Inc. and four leading cancer centers have established the Actionable Genome Consortium (AGC), an initiative that will recommend openly published standards for widespread use of next-generation sequencing to aid in treatment decision for cancer patients. Specifically, the AGC will aim to define the principles and content of the “cancer actionable genome,” a comprehensive description of genomic alterations that define individuals’ tumors. The founding members include, other than Illumina, the Dana-Farber Cancer Institute, Fred Hutchinson Cancer Research Center, MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center. The AGC will publish a list of actionable events—including best practices regarding biopsy samples, performance standards for sequencing, guidelines for clinical reports and standards for genetic variants—and include a research arm for collaborative, cross-institutional projects regarding leading challenges in molecular oncology.

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