UGA study produces gastric cancer diagnostic test
June 2011

ATHENS, Ga.—According to a pair of studies recently published by researchers at the University of Georgia (UGA) in PloS ONE, certain proteins excreted in urine can denote the existence of gastric cancer, the second deadliest form of cancer in the world. Of the urine samples from 21 healthy people, all but two had the protein endothelial lipase, while only one of the 21 cancer patients' samples registered a relatively high level of the protein. The researchers hope to produce urine tests similar to home pregnancy tests that can detect the protein. Ying Xu, lead author of the studies, biochemistry and molecular biology professor and director of UGA's Institute of Bioinformatics, says that "in theory, the methodology that we developed should be applicable to other cancers." The study received support from the UGA President's Venture Fund, the Office of Vice President for Research, the Georgia Cancer Coalition, the Georgia Research Alliance, Jilin University and the National Institutes of Health.

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