In The Spotlight
DDNews Cancer Research Exclusive
 
 
Recent work with nanoparticles offers a new approach to photo-thermal cancer therapies
 
(Photo credit: University of Toronto)
 
The PEARLs (Photothermal Enhancing Auto-Regulated Liposomes) were developed by Dr. Gang Zheng of the Princess Margaret Cancer Centre and University of Toronto and colleagues, who say they overcome traditional roadblocks to penetrate deeper into tumors.
 
 
NEWS
Scientists at Cornell University found that Cas3 can delete long sequences of DNA, while a Wellcome Sanger Institute team and collaborators used CRISPR to identify 600 promising gene targets for drug development
 
CrownBio and HUB ink license agreement to offer their PDX and organoid platforms together
 
Australia’s Noxopharm unveils preclinical results on idronoxil
 
Existing drug may successfully treat aggressive tumor
 
We look at FLIP, STING and other potentially groundbreaking areas of oncology therapeutics R&D
 
Merck's Keytruda racks up yet another FDA approval—this time as a combination with Inlyta for patients with renal cell carcinoma
 
Researchers pinpoint a mechanism by which colorectal cancer cells can evade immunotherapy
 
MOR208 clinical trial results promising and drug is on fast track to FDA approval, company says
 
 
FEATURES
 
 
Glioblastoma remains a difficult cancer to treat, but the brain malignancy is seeing increasing attention in R&D
 
OPINION
by Charles River Laboratories
Drs. Ulrike Herbrand, Christopher Sucato and Alvaro Jorge Amor of Charles River Laboratories discuss the challenges of bringing antibody-drug conjugates to market

by S. Anderton and M. Millar
There are currently three main approaches to characterizing the immune landscape of solid tumors: transcriptional profiling, single-cell cytometric analyses and histology; each of these disciplines brings its own benefits and, with rapid technological advances, powerful datasets are now achievable.

by Kevin Bobofchak of Lonza
A look at the importance of Th17 cells for drug discovery and look at how the use of specialized methods to confirm cellular identity provides a level of validation that has not previously been available


 
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