Back To: Home : Featured Technology : Functional Genomic Screening


Complete Genomics, Inova Health System to sequence the genomes of 500 babies and parents
October 2011

MOUNTAIN VIEW, Calif.Complete Genomics Inc. and Inova Health System announced in September that they will sequence 1,500 genomes from 500 babies and their parents. The goal of this project is to identify prognostic, diagnostic and therapeutic targets for pre-term delivery and potentially other obstetrics associated abnormalities.
The partnership is part of a pilot program with the Inova Translational Medicine Institute (ITMI), a not-for-profit research institute within the Inova Health System in Falls Church, Va., aimed at translating clinical research into actual care programs using genomically driven patient care often referred to as personalized medicine.

"Complete Genomics is a natural choice as our sequencing partner for this new program," said John Niederhuber, CEO of the ITMI, in a statement. "We are confident that Complete Genomics can manage a large project of this type efficiently and produce the consistent, high-quality sequencing data that we need to be able to understand the subtle genetic changes that contribute to pre-term delivery."

"The Inova Translational Medicine Institute is truly an innovator in the delivery of patient care, striving to not only understand the genomic makeup of patients, but also to customize care to the individual to help prevent or manage their diseases," added Dr. Clifford Reid, chairman, president and CEO of Complete Genomics. "We view this as an important opportunity for our sequencing service to potentially help create new treatment options for some of the smallest and sickest patients in the hospital."

The ITMI has already begun collecting DNA samples for Complete Genomics to begin sequencing. Complete Genomics will begin delivering variant reports to ITMI as early as the fourth quarter and expects to finish a large majority of the 1,500 genomes in the first quarter of 2012.

These results will detail how the genomes of pre-term delivery babies from Inova Fairfax Hospital's Joint Commission certified Neonatal Intensive Care Unit compare with reference genomes. They will include information about the SNPs, insertions/deletions, copy number variations and structural variations included in each DNA sample, together with the read alignments supporting those calls, coverage information and quality scores. In addition to sequence-based data, the ITMI will also generate epigenomic, expression and micro RNA data on each sample. Data from Inova Health System's electronic medical record system will support the ITMI's outcomes-based research.

Complete Genomics is a human genome sequencing company. Its Complete Genomics Analysis Platform combines the company's proprietary human genome sequencing technology with advanced informatics and data management software.

Inova Health System is a not-for-profit health care system based in Northern Virginia that consists of hospitals and other health services, including emergency- and urgent-care centers, home care, nursing homes, mental health and blood donor services, and wellness classes. Governed by a voluntary board of community members, Inova's mission is to improve the health of the diverse community it serves through excellence in patient care, education and research.

Established in 2010 as a research organization, the ITMI is part of the Inova Health System. The ITMI's mission is to translate new knowledge from genomics and the molecular sciences into value-added interventions and strategies that enable Inova's diverse physician community to deliver state-of-the art patient care and disease risk reduction to its broad patient base.



1000 N West Street, Suite 1200,
Wilmington, Delaware, 19801
Ph: 888-781-0328 |  Fax: 705-528-0270
© Copyright 2020 Old River Publications LLC. All righs reserved.  |  Web site managed and designed by OffWhite.