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NIH grants $9 million to Medical College researcher
November 2011
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MILWAUKEE, Wis.A Medical College of Wisconsin researcher has won a five-year, $9 million grant from the U.S. National Institutes of Health to fund his work on the use of stem cells and genetics to study cardiovascular disease. Stephen A. Duncan, director of the regenerative medicine program at the Medical College, will collaborate with Daniel J. Rader and Edward Morrisey, both of the University of Pennsylvania (UPenn) . Rader heads the Division of Translational Medicine and Human Genetics at UPenn, and Morrisey is a professor of medicine and cell and developmental biology. The researchers will work with fat cells from 300 patients with specific genetic profiles, sending the cells back to their embryonic origin before converting them to liver cells. Their hope is that examination of these cells will shed light on why some patients with specific genetic mutations are predisposed to producing high levels of plasma lipids.

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