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Plasticell and Sigma-Aldrich to produce turnkey solution for stem cell research
January 2011
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LONDON—Plasticell and Sigma-Aldrich recently announced that they are collaborating on the creation of a novel turkey solution for stem cell research. Sigma-Aldrich will use its CompoZr Zinc Finger Nuclease Technology to engineer various human stem cell lines that enable tracking of differentiation to specific mature cell types via fluorescent reporters, integrated directly into developmentally expressed genes. Plasticell will then use these cell lines in its CombiCult high-throughput screening system to develop novel stem cell differentiation protocols. Plasticell will own resulting protocols for high efficiency, directed differentiation of stem cells, with Sigma-Aldrich marketing the reporter stem cell lines. Cells and media may be commercialized together in kits, while reporter cell lines can be linked to specific CombiCult screens for optimised differentiation of human embryonic stem cells or induced pluripotent cells. Financial terms were not disclosed.


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