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Soluble form of basement membrane
December 2010
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Trevigen Inc.  
Trevigen has added a stem cell-qualified basement membrane extract (BME), PathClear, to its lineup. It is a soluble form of basement membrane purified from Engelbreth-Holm-Swarm tumor. The extract forms a reconstituted basement membrane mainly comprised of laminin, collagen IV, entactin and heparin sulfate proteoglycan. Cultrex stem cell-qualified BME provides an effective feeder-free surface for the attachment and maintenance of human embryonic stem cells in a pluripotent state, thereby enabling its use for growth promotion or for study of stem cell differentiation. This is demonstrated by the presence of Oct-4 and Nanog in H9 human embryonic stem cells grown on Cultrex stem cell-qualified BME.   
 
Trevigen Inc.
(312) 216-2800
www.trevigen.com
 

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