Complex cell- and bead-based assays are made simple and fast with the CellSimple Cell Analyzer. This instrument combines a 488 nm laser, dual photomultiplier tubes, Coulter principle- based cell measurements and onboard software to provide easy-to-run applications and data analysis. Moreover, the instrument relies on disposable cassettes for sample handling, which alleviates the need for flow cell cleaning and fluidics maintenance, and the instrument is small enough to be portable between the lab bench and the hood.