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High-throughput in-vivo CNS pharmacology screening
October 2013
by Bruce Poorman  |  Email the author
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Charles River Discovery Research Services
 
High-throughput in-vivo CNS pharmacology screening provides rapid, tailor-made lead validation service using selected in-vivo and ex-vivo assays. Locomotor activity, catalepsy test, MRI Imaging and supportive PK and receptor occupancy assays reveal PK/PD dynamics of new molecules with administration routes from traditional to systemic and brain IT/ICV/IP. Endpoint sampling for tissue, plasma and CSF enables additional mechanistic characterizations.

Charles River Discovery Research Services

www.crl.com 
+35 8 17 3680 801

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