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Bristol-Myers Squibb to acquire Inhibitex for $2.5 billion
01-10-2012
SHARING OPTIONS:
NEW YORK & PRINCETON, N.J. & ATLANTA—Bristol-Myers
Squibb Co. (BMS) and Inhibitex Inc. have signed a definitive agreement under
which BMS will acquire Inhibitex for approximately $2.5 billion, a price that has
been approved by the boards of directors of both companies, with Inhibitex’s
board agreeing to recommend that Inhibitex’s shareholders tender their shares
in the offer. In addition, shareholders with beneficial ownership of
approximately 17 percent of Inhibitex’s common stock have entered into
agreements with BMS to support the transaction and to tender their shares in
the tender offer.
Inhibitex is a clinical-stage biopharmaceutical
company dedicated to developing innovative products that can treat or prevent
serious infections, and its primary focus is on the development of
nucleotide/nucleoside analogs for the treatment of infection by the hepatitis C
virus (HCV). The company’s lead HCV asset is INX-189, an oral nucleotide
polymerase (NS5B) inhibitor in Phase II development that reportedly has
exhibited “potent antiviral activity, a high barrier to resistance and
pan-genotypic coverage.”
According to BMS, nucleotides/nucleosides are
emerging as an important class of antivirals that may play a critical role as
the backbone of future direct-acting, antiviral-only combination approaches to
HCV treatment.
“The acquisition of Inhibitex builds on
Bristol-Myers Squibb’s long history of discovering, developing and delivering
innovative new medicines in virology and enriches our portfolio of
investigational medicines for hepatitis C,” said Lamberto Andreotti, CEO of
BMS, in a news release about the deal. “There is significant unmet medical need
in hepatitis C. This acquisition represents an important investment in the
long-term growth of the company.”
Many market-watchers think the acquisition of
Inhibitex’s HCV pipeline is important specifically to offset expected losses
from its blood-thinning drug Plavix (clopidogrel), which posts estimated annual
sales of between $6 billion and $7 billion, when it loses patent protection in
May in the United States and in early 2013 in Europe. BMS co-markets Plavis in partnership
with Sanofi.
Merchant Securities analyst Navid Malik says BMS “needs
to buy its way out of trouble” and adds that hepatitis C is “a very competitive
space now and this is a sign that Bristol-Myers Squibb wants to be a part of
that.”
In fact, in November, Gilead Sciences Inc. announced a definitive agreement to acquire Pharmasset Inc. for $11 billion to add a strong HCV presence in the
market to complement its reputation in HIV treatment. Pharmasset currently has
three clinical-stage product candidates for the treatment of chronic hepatitis
C virus (HCV) advancing in trials in various populations.
“The world is moving toward an all-oral regimen
for hepatitis C, and Bristol-Myers, which is strong in antivirals, seems like
it wants to be a part of that,” notes Les Funtleyder, a healthcare strategist at
Miller Tabak & Co., echoing Malik’s insights.
“This transaction puts INX-189 and the company’s
other infectious disease assets in the hands of an organization that can more
optimally develop them and which believes as strongly as we do in INX-189’s
potential in the treatment of chronic HCV,” said Russell Plumb, president and CEO
of Inhibitex, in an official statement. “Bristol-Myers Squibb’s expertise in
antiviral drug development, and its existing complementary portfolio, will
assure that the potential of INX-189 is realized as part of future oral
combination therapies for millions of patients in need around the world.”
“Bristol-Myers Squibb continues to drive advances
in the field of hepatitis C research and development through internal
development and selective partnerships,” notes Dr. Elliott Sigal, executive
vice president, chief scientific officer and president of R&D for BMS. “The
addition of Inhibitex’s nucleotide polymerase inhibitor to our own promising
portfolio, which includes other direct-acting antivirals, brings additional
options to develop all-oral regimens with better cure rates, shorter duration
of therapy and lower toxicity than the current standard of care.”
The transaction is expected to be dilutive to
earnings for BMS through 2016, with an expected impact on earnings per share of
approximately $0.04 in 2012 and approximately $0.05 in 2013.
Under the terms of the definitive agreement, BMS
will commence a cash tender offer to purchase all of the outstanding shares of
Inhibitex’s common stock for $26 per share. The closing of the tender offer is
subject to customary terms and conditions, including the tender of a number of
shares that constitutes at least a majority of Inhibitex’s outstanding shares
of common stock (on a fully diluted basis) and expiration or termination of the
waiting period under the Hart-Scott-Rodino Antitrust Improvements Act. The
agreement also provides for the parties to effect, subject to customary
conditions, a merger to be completed following the completion of the tender
offer which would result in all shares not tendered in the tender offer being
converted into the right to receive $26 per share in cash. The merger
agreement contains a provision under which Inhibitex has agreed not to solicit any
competing offers for the company. BMS will finance the acquisition from its
existing cash resources. The companies expect the tender offer to close
approximately thirty days after commencement of the tender offer.
This offer represents a premium of approximately
126 percent of Inhibitex’s share price over the previous 20 trading days, putting
it on record as the second-largest premium for a biotechnology or
pharmaceutical company worth more than $500 million, according to data compiled
by Bloomberg since 1999. The record is currently held by Genzyme Corp. for its
2006 deal for AnorMed Inc., with a 162 percent premium.
“The deal seems a bit expensive for an early-stage
compound, but there is scarcity value,” notes Funtleyder, whose fund holds BMS
shares.
As many as 170 million people globally carry the
hepatitis C virus, and current drugs, given through injection, can have side
effects that make therapy difficult to endure. The next generation is designed
to be taken as pills that can offer a higher cure rate and fewer side effects.
Code: E01111201 Back |
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