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Integrated testing strategy for the evaluation of environmental contaminants
January 2010
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Roche
 
In collaboration with the Alberta Centre for Toxicology (ACFT), the University of Calgary and ACEA Biosciences Inc., Roche has co-developed the xCELLigence System, a cell substrate impedance measurement based instrumentation and software that integrates micro electronics and cell biology. Among many other biomedical research applications, it is ideally suited for toxicology uses because it can dynamically monitor cell growth and/or death in cultures exposed to environmental chemicals. The pattern of cell growth/death can provide important mechanistic information about the contaminants. Other such parameters as the inhibitory concentration can also be measured, and together with existing information about the chemicals, it can be used to develop an integrated health risk assessment model.
 
Roche
(800) 262-1640
 

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