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SENS-401 supports hearing recovery
February 2019
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MONTPELLIER, France—Sensorion recently saw data illustrating the otoprotective potential of its SENS-401 compound published in Otology & Neurology. The data in question focused on the twice-daily oral administration of SENS-401 in preclinical models of rats with severe acoustic trauma-induced hearing loss. Using auditory brainstem response, distortion product otoacoustic emissions and histology, the research team saw that the aforementioned dosing regimen was optimal for hearing protection, and saw the treatment provide statistically significant hearing protection and recovery even as much as 96 hours after acoustic trauma. SENS-401, R-azasetron besylate, is a small-molecule drug candidate being advanced for the protection and preservation of inner ear tissue.

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