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Nicox, Novliq ink ophthalmic collaboration
February 2019
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SOPHIA ANTIPOLIS, France—Nicox SA and Novaliq GmbH have struck up a research collaboration to develop novel topical ophthalmic formulations of Nicox’s nitric oxide (NO)-donating PDE5 inhibitors based on Novaliq’s water-free enabling EyeSol technology, in pursuit of therapeutics to lower intraocular pressure (IOP). Novaliq will develop and characterize novel formulations for the lead series of NO-donating PDE5 inhibitor compounds with its EyeSol technology. Should they prove successful, Nicox will test the formulations’ ability to lower IOP in preclinical models. No financial terms were disclosed, but the companies will jointly own any newly developed intellectual property that results from this agreement. This deal complements Nicox’s recent decision to focus on topical delivery of NO-donors and their potential in glaucoma.

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