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TruGraf can identify stable kidney transplant patients
January 2018
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MANSFIELD, Mass.—Molecular diagnostics company Transplant Genomics Inc. recently had a report published in the Journal of Transplantation Technologies & Research detailing the use of its TruGraf blood test on 125 kidney transplant recipients with known stable renal function. Each had surveillance biopsies performed at the same time, ones that confirmed normal histology. The test was able to identify almost 90 percent of patients who were adequately immunosuppressed and could have avoided the biopsy. The retrospective data modeling study showed that TruGraf testing of blinded samples saw an overall sensitivity of 88 percent with a positive predictive value of 86 percent.
 
“The results of this study indicate clinical utility of TruGraf testing as a non-invasive alternative to surveillance “protocol” biopsies to confirm immune quiescence in kidney transplant recipients with stable renal function,” said Dr. M. Roy First, chief medical officer at TGI and lead author of the study.

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